Mr. Narayan Devkota
Chairman
Research Center for Applied Statistics - RECAS
P.O.BOX 15145

Kathmandu
15145 Nepal
T.: 977 1 4351242
Fax: 977 1 4423542
info@researchnepal.org

 Research Center for Applied Statistics ( RECAS) is a research center for the Health and medical research in different diseases that exist in Nepal.  RECAS in co-operation with Institute of Medicine,Tribhubhan University ( Department of Anatomy, Department of Radiology, Department of Neurology and Department of Pharmacology ), Institute of Ayurvedic Medicine and Institute of natural medicine seek  to investigate in Neurodegenerative  disorder, cognitive disorders and dementia in our area for both clinical activities to diagnosis of Alzheimer diseases and  herbal and Traditional Chinese medicine treatment  including Accupuncture  that exists in Nepal in both preventative and curative mode. The team focus on the ethnopharmacological approach to identify potential new drugs of Cognitive Disorder including Alzhimer diseases. The principal field of Investigation is the evaluation of Alzheimer diseases in environment especially in higher altitude by using pharmacological treatment after prevalence’s of AD, clinical  diagonosis of patients with different types of Dementia, especially using Herbal Medicine, Traditional Chinese medicine  and complementary medicine with Naturopathy. The team is cossist of the following Member. Prof Dr R.P. Uprite, - Physician,  Prof. Dr Taraman Amayta – specialist of Alzhimer Diseases, Dr Dhurba Adhikari – neurosurgeon and expert of Alzheimer’s diseases. Dr, Thakur Duwadi – Specialist of herbal medicine for alzhimer treatment , Prof dr. Surya  Bahadur karki- Naturopath, Dr – S. Pandey – Music therapist, Narayan devkota – statistician for data analysis and co-ordination of such team are Involved. 

The diagnosis of Mild Cognitive Impairment ( MCI) and Alzhimer disease is very difficult through symptoms only but can identify through  radiology test as well. After diagnosis of such patients having Alzheimer diseases with cognitive disordered, neurodegenerative diseases. These patients are in case control study under existing allopathic Chinese medicine as  common for them and additional dose of herbal medicine, traditional Chinese medicine with acupuncture  with Music therapy are used for their treatment. These Natural remedies such as Ayurvedic, Naturopathy ( Meditation ) and different of herbs as food and drugs supliment will given for the patient in  low cost have no side effect for the patients. After having the treatment of such patients we will refer for the follow up  them by using herbal and  traditional Chinese medicine, meditation and Acupunture for completely recovery of Memory, Enhancing cognitive , anti againg and  many other neurodegenerative diseases like hypertention,inflammation, oxidative stress, .

 There is ethnopharmacology approach  has provided lead to identify potential new herbal drugs for cognitive Disorder. Plants and their constitutes with pharmacological activities that may relevant for the treatment of cognitive disorder including enhansment of cholinergic function of central nervious system, anti-Inflammatory, antioxident activities . Many herbal plants have many drugs which are essential for the Alzhimer’s diseases and Mild cognitive Impairment. Eg. Anti- Che ( anticholinesterase. Alkaloids Isolated from the plants have been used for cognitive enhancing, Galantamine – Isolated from Lycoris radiate herbs which is also used for cognitive enhancing or antiagening, and Galanthus nivalis anve anti- dementis effect on using. Our plan is is to use orka, charungli, Bitter melon , angular loofah and neem plant are used as herbal drugs in our investigation.

The team of Haematologists participant from RECAS unit  identify the case of the patients of Alzheimer Diseases with Mild Cognitive Impairment ( MCI ) on the basis of  symptoms by using technology ( MRI, CT scan and EEG ) from the 4500 patients as a sample. From the 4500 patients sample patients in the age above 45 will consider in our sample on the basis of life expectancy of Nepalese,135 patients are taken as case control study under treatment under Chinese Medicine with Meditation. These patient are split into three category as Block in which Chinese medicine, Meditation with Music therapy in A. In block B Chinese medicine, Meditation  with Herbal ( Ayurvedic)  medicine are taken into account and in Block C, Chinese medicine, Meditation with acupuncture and acupressure are taken as a account in our study. These are carry out in 700m height for the A Block  , 1500m height for block B patients and 2500 m height for Block C category patient in Terai, Hills and Mountain area. In each six month the effectiveness of such things are taken into account. The food supplements stuff are consider for all case as a homeopathy part of treatment.

The Longitudinal case control  study will be consider for  evaluation for  Alzheimer disease on using the above treatment. Follow up treatment will be given for the patient on the basic of our finding on  Chinese medicine, Herbal medicine, Acupuncture and Acupressure, Meditation with music therapy .

We propose to search the best way of treatment of AD to predict who are the persons with MCI who progress to dementia through the identification of specific causative sequence  Improve variations and the analysis of cause of  environmental factor  and side effect less alternative medicine  with Chinese medicine in AD through Ethnopharmacology activities.

Research center for applied Statistics ( RECAS) is a Social  Research organization for Health, Education, Agriculture research. It conducts survey research and suggest to implement the survey finding or tries to implement such finding for the benefit of rural, downtrodden people. The health research team is well qualified for doing the in medical research. The principal field of Investigation is to evaluation of Alzhimer diseases through chinese medicine including Herbal, meditation, Music therapy in different altitudes.

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